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Elbaz PIC-CVI Lab

The Elbaz Personalized & Integrative Computational Cardiovascular Imaging (PIC-CVI) research lab is within the Northwestern Radiology Department and focuses on developing novel advanced computational MRI analysis techniques to enable personalized & integrative comprehensive assessment of complex cardiovascular diseases. This achieved by employing advances interdisciplinary computational imaging techniques spanning computer science, cardiovascular imaging, applied fluid dynamics and translational cardiovascular clinical research. Example interests include developing methods for noninvasive evaluation of advanced hemodynamics (e.g. from 4D Flow MRI), precise quantification of high-dimensional physiologic & structural imaging data (e.g. high-dimensional scalar, vector and tensor field data from 3D LGE, Diffusion MRI, Tissue Phase Mapping, 4D Flow, T1 & T2 mapping etc.) and effective integration of MRI with other imaging modalities (e.g. Electrophysiology, CT, PET, Echo, etc.). Such methods are utilized to revealing new insights into underlying cardiovascular pathophysiologic mechanisms and developing novel diagnostic & predictive markers for better risk stratification in adult and congenital cardiovascular disease.

 

Mohammed S.M. Elbaz, PhD

Director of the Personalized & Integrative Computational Cardiovascular Imaging (PIC-CVI) Lab

Assistant Professor of Radiology – Computational Cardiovascular Imaging

Department of Radiology Northwestern University Feinberg School of Medicine

737 N. Michigan Avenue Suite 1600, Chicago Illinois 60611

 
Education:

2018 Postdoctoral Research Associate, Radiology Department, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA

2017 Postdoctoral scholar, Computer Science Department, University of Calgary, Calgary, Canada

2016 Diploma (as part of PhD studies) from the Advanced School for Computing and Imaging (ASCI), Delft, the Netherlands

2016 PhD in Biomedical Imaging, Leiden University, Leiden, the Netherlands

 
Selected Publications (Full list can be found here: ORCID    Google Scholar   Pubmed)
  1. Mohammed S.M. Elbaz, Michael B. Scott, Alex J Barker, Patrick McCarthy, Chris Malaisrie, Jeremy D Collins, Robert O. Bonow, James Carr, Michael Markl. “Four-dimensional virtual Catheter: noninvasive assessment of intra-aortic hemodynamics in bicuspid aortic valve disease”. Radiology 2019
  2. Elbaz, M. S., van der Geest, R. J., Calkoen, E. E., de Roos, A., Lelieveldt, B. P., Roest, A. A., & Westenberg, J. J. (2017). Assessment of viscous energy loss and the association with three‐dimensional vortex ring formation in left ventricular inflow: In vivo evaluation using four‐dimensional flow MRI. Magnetic resonance in medicine77(2), 794-805.
  3. Elbaz, Mohammed SM, Boudewijn PF Lelieveldt, and Rob J. van der Geest. “Hierarchical Shape Distributions for Automatic Identification of 3D Diastolic Vortex Rings from 4D Flow MRI.” Medical Image Computing and Computer-Assisted Intervention–MICCAI 2015. Springer International Publishing, 2015. 467-475.
  4. Kamphuis V*, Elbaz MS*, van den Boogaard PJ, Kroft LJ, van der Geest RJ, de Roos A, Helbing WA, Blom NA, Westenberg JJ and Roest AA. Disproportionate Intraventricular Viscous Energy Loss in Fontan Patients: analysis by 4D Flow MRI. European Heart Journal–Cardiovascular Imaging. 2018; (* shared first-author).
  5. Mohammed SM Elbaz, Emmeline E Calkoen, Jos JM Westenberg, Boudewijn PF Lelieveldt, Arno AW Roest, Rob J van der Geest: Vortex flow during early and late left ventricular filling in normal subjects: quantitative characterization using retrospectively-gated 4d flow cardiovascular magnetic resonance and 3 dimensional vortex core analysis. Journal of Cardiovascular Magnetic Resonance 2014 16:78.
  6. Mohammed S. ElBaz, Ahmed S. Fahmy. “Active Shape Model with Inter-profile Modeling paradigm for Cardiac Right Ventricle Segmentation”, Medical Image Computing and Computer Assisted Intervention (MICCAI) 2012, Nice, France.
  7. Kamphuis, Vivian P., Jos JM Westenberg, Roel LF van der Palen, Pieter J. van den Boogaard, Rob J. van der Geest, Albert de Roos, Nico A. Blom, Arno AW Roest, and Mohammed SM Elbaz. (2018) “Scan–rescan reproducibility of diastolic left ventricular kinetic energy, viscous energy loss and vorticity assessment using 4D flow MRI: analysis in healthy subjects.” The international journal of cardiovascular imaging: 1-16.
  8. Liang Zhong, Eric Schrauben, Julio Garcia Flores, Sergio Uribe, Stuart Grieve, Mohammed S. M. Elbaz, Alex Barker, Julia Geiger, Sarah Nordmeyer, Alison Marsden, Marcus Carlsson, Ru-San Tan, Pankaj Garg; Jos Westenberg, Michael Markl, Tino Ebbers “Intracardiac 4D flow MRI in congenital heart disease: Recommendations on behalf of the ISMRM Flow & Motion Study Group”. Journal of Magnetic Resonance Imaging 2019
  9. S. M. ElBaz, B. P. F. Lelieveldt, J. J. Westenberg and R. J. van der Geest, “Automatic Extraction of the 3D Left Ventricular Diastolic Transmitral Vortex Ring from 3D Whole-Heart Phase Contrast MRI using Laplace-Beltrami Signatures”, Statistical Atlases and Computational Models of the Heart (STACOM),Springer Berlin Heidelberg 2014
  10. Trung Bao Le, S.M. Elbaz, Rob J. Van der Geest and Fotis Sotiropoulos, Qualitative and quantitative cross-evaluations of left ventricular hemodynamics in a healthy subject: image-guided simulation and four-dimensional MRI data. Flow, Turbulence and Combustion. 2019

 

Patents
  1. US. patent pending: application# 62/760,011 (Filing Data 11/12/2018 by Northwestern INVO): Mohammed S.M. Elbaz, Michael Markl “Noninvasive Quantitative Flow Mapping Using a Virtual Catheter Volume”.
  2. US. patent pending: application# 62/892,234 (Filing Data 08/27/2019 by Northwestern INVO): Mohammed S.M. Elbaz, Michael Markl “Co-Expression Signatures Method for Quantification of Physiological and Structural Data”.
 
Selected Honors & Awards

2019    Summa Cum Laude Merit Award from ISMRM 27th Conference, 11-16 May, Montreal, Canada for the abstract ” Stochastic Flow Co-expression Signatures: A novel concept for volumetric 4D flow assessment with application to aortic valve disease”. ISMRM is the international society for magnetic resonance in medicine.

2019    Research Presentation Award from the ISMRM Cardiac MR Study Group, ISMRM 27th Conference, 11-16 May, Montreal, Canada for the abstract ” Stochastic Flow Co-expression Signatures: A novel concept for volumetric 4D flow assessment with application to aortic valve disease”.

2019    Educational Stipend Award, ISMRM 27th Conference, 11-16 May, Montreal, Canada

2019    Early Career Award Finalist, Society of Cardiovascular Magnetic Resonance (SCMR) 22nd Scientific meeting, February 6 – 9, 2019, Bellevue, USA (2019) for the abstract titled:“4D Flow vCath: A novel virtual catheter technique for assessing hemodynamics in aortic valve disease”.

2019     Best moderated e-poster Finalist in the SCMR 22nd Scientific meeting, Bellevue, USA for abstract titled “Impact of pulmonary hypertension on viscous energy loss, kinetic energy and vorticity in the right heart: A pilot 4D Flow CMR study”.

2019     Travel Award from the Society of Cardiovascular Magnetic Resonance (SCMR) 22nd Scientific meeting, Bellevue, USA

2019     Travel Stipend Award from the 27th annual conference of International Society of Magnetic Resonance in Medicine (ISMRM), 11-16 May 2019, Montreal, Canada

2018      2-year America Heart Association (AHA) postdoctoral fellowship: “4D  Flow  vCath:  virtual  Catheter  for  Assessing  Hemodynamics  in  Bicuspid  Aortic  Valve” (awarded from the first submission)

2018     Travel award from 71st annual meeting of the American Physical Society Division of Fluid Dynamics, Atlanta, USA November 18-20, 2018

2018     Travel Award from the 30th annual conference of the Society of Magnetic Resonance Angiography (SMRA), Glasgow, Scotland

2018     Selected among only 8 PhD participants for the RSNA (Radiological Society of North America) ITARSc Program for junior scientists

2018     My senior-authored paper appeared as the cover of the International Journal of Cardiovascular Imaging (June issue).

2015     Magna Cum Laude Merit Award from ISMRM 23rd Conference, Ontario, Canada for the abstract “Contribution of early and late filling vortex rings to normal left ventricular flow”. ISMRM is the international society for magnetic resonance in medicine.

2012        Travel Award from MICCAI conference 2012, Nice, France.

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